Advanced Plus NICC Test (NIPT) in Johor Bahru
Comprehensive Non-Invasive Prenatal Test (NIPT)
The Advanced Plus NICC Test (NIPT) is a comprehensive non-invasive prenatal test (NIPT) designed for expectant parents who want expanded fetal genetic screening together with maternal genetic carrier screening.
This NIPT analyses fetal cell-free DNA (cfDNA) from a simple maternal blood sample and can be performed from 10 weeks of pregnancy onwards. It is safe for the baby and carries no miscarriage risk.
Advanced Plus NICC is commonly chosen by parents who want deeper reassurance without going all the way to the Ultimate NIPT package.
What’s Included in This NIPT Screening?
Blood Test (NICC / NIPT)
Screens the baby for common chromosomal trisomies, including:
• Trisomy 21 (Down Syndrome)
• Trisomy 18 (Edwards Syndrome)
• Trisomy 13 (Patau Syndrome)
Sex Chromosome Aneuploidies
(Sex Chromosome Abnormalities)
Screens for abnormalities involving sex chromosomes, including:
• Turner Syndrome (XO)
• Triple X Syndrome (XXX)
• Klinefelter Syndrome (XXY)
• Jacob’s Syndrome (XYY)
• Plus 22 other chromosomal aneuploidies
5 Microdeletion Syndromes
(Microdeletion Analysis)
Screens for selected clinically significant microdeletion syndromes, including:
• DiGeorge Syndrome (22q11.2 Deletion)
• Angelman Syndrome
• Prader–Willi Syndrome
• Cri-du-Chat Syndrome
• 1p36 Deletion Syndrome
Gender Identification
Fetal gender can be identified from 10 weeks onwards,
Maternal Genetic Screening
(Maternal Carrier Screening)
Advanced Plus NICC includes maternal screening for 18 single-gene recessive disorders, such as:
Alpha Thalassemia, Beta Thalassemia, G6PD Deficiency, Galactosemia, Phenylketonuria, Citrin Deficiency, Pompe Disease, Wilson Disease, 5 Alpha-reductase Deficiency, Pendred Syndrome, Primary Carnitine Deficiency, Niemann–Pick Disease, Cystic Fibrosis, Charcot–Marie–Tooth Disease, Polycystic Kidney Disease, Hemophilia A, Adrenoleukodystrophy, and Ornithine Transcarbamylase Deficiency.
Doctor Consultation
A consultation with our Klinik Caring doctors to:
• Explain your NIPT results clearly
• Discuss fetal and maternal findings
• Advise on further testing or follow-up if required
Why Choose Advanced Plus NICC (NIPT)?
The Advanced Plus NICC Test (NIPT) in Johor Bahru is ideal for parents who want broader fetal screening plus maternal genetic insight, without moving to the most extensive single-gene fetal panels.
It is commonly chosen by parents who:
• Want expanded chromosomal and microdeletion screening
• Wish to understand maternal genetic carrier risks
• Have a family history of inherited conditions
• Want more reassurance than Standard Plus NIPT
• Prefer a balanced yet comprehensive NIPT option
This non-invasive NIPT blood test integrates smoothly into routine antenatal care and provides early, meaningful reassurance from 10 weeks onwards.
At Klinik Caring, we prioritise clear explanations, thoughtful counselling, and personalised care throughout your pregnancy journey.
Frequently Asked Questions (FAQ)
What is the Advanced Plus NICC Test (NIPT)?
Advanced Plus NICC is a comprehensive non-invasive prenatal test (NIPT) that includes fetal chromosomal screening, microdeletion analysis, and maternal genetic carrier screening.
When can I do the Advanced Plus NICC (NIPT)?
The test can be performed from 10 weeks of pregnancy onwards.
Is Advanced Plus NICC (NIPT) safe?
Yes. It is a maternal blood test only and poses no risk to the baby.
What is the difference between Advanced NICC and Advanced Plus NICC?
• Advanced NICC (NIPT)
Screens fetal chromosomal abnormalities and microdeletion syndromes only.
• Advanced Plus NICC (NIPT)
Includes almost everything in Advanced NICC plus maternal screening for 18 single-gene recessive disorders.
Who should consider Advanced Plus NICC?
It is suitable for parents who want expanded fetal screening and maternal carrier information, especially those planning future pregnancies or with family history concerns.
Does NIPT replace ultrasound scans?
No. NIPT is a screening test and does not replace routine ultrasound scans or standard antenatal check-ups.
Where can I do the Advanced Plus NICC Test (NIPT) in Johor Bahru?
The Advanced Plus NICC Test (NIPT) is available at Klinik Caring, serving patients from Skudai, Impian Emas, and across Johor Bahru.



